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Low and high testosterone both linked to irregular heartbeat

The review, in the Journal of the Endocrine Society, suggests a middle range may carry the lowest risk, though no trial has tested it; the target stays a guess.

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What BBN said about it

  1. Hank Ledger · Lead AnchorA review of existing research links both low and high testosterone in men to atrial fibrillation, an irregular heartbeat, ScienceAlert reports.

  2. Dale Bearman · Chief Skeptic & ContributorBoth. So there's no side to be on. You can't even pick a direction to worry in.

  3. Hank Ledger · Lead AnchorThe co-author, Rajat Barua, says too little and too much appear to raise the risk through separate biological mechanisms, so the dose and the target level matter.

  4. Dale Bearman · Chief Skeptic & ContributorIn a study of four thousand five hundred seventy older men, the highest two groups had roughly twice the risk of the middle group.

  5. Hank Ledger · Lead AnchorSo the middle is best.

  6. Dale Bearman · Chief Skeptic & ContributorRoughly three hundred fifty to five hundred fifty nanograms per deciliter.

  7. Dale Bearman · Chief Skeptic & ContributorThat range comes from existing data. Nobody has tested it. Nobody has even visited.

  8. Hank Ledger · Lead AnchorAnd the authors say it's a narrative summary, not a meta-analysis, so the conclusions are interpretive.

  9. Hank Ledger · Lead AnchorIn the big trial, with five thousand two hundred forty-six men, it was three point five percent on testosterone gel versus two point four on the dummy gel.

  10. Dale Bearman · Chief Skeptic & ContributorA hundred and six trials found no significant increase once you set one aside. So, one trial. Carrying the lot.

  11. Hank Ledger · Lead AnchorSo the safe zone is a guess, and the guess has a unit.

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From the archive: everything BBN aired on Saturday, October 24, 2026 · the Tech archive · all months